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. 1973 Jul;4(1):69–71. doi: 10.1128/aac.4.1.69

Effect of Oral Tetracycline on the Occurrence of Tetracycline-Resistant Strains of Escherichia coli in the Intestinal Tract of Humans

Dwight C Hirsh 1, Glenna C Burton 1, Donald C Blenden 1
PMCID: PMC444507  PMID: 4598847

Abstract

Serial samples of feces from normal human subjects were analyzed for tetracycline-resistant strains of Escherichia coli. Subjects were found to be excreting tetracycline-resistant strains in amounts fluctuating with time. Ingestion of tetracycline increased both the number of individuals excreting tetracycline-resistant strains of E. coli and the proportion of the total E. coli isolates resistant to the antibiotic.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Datta N., Faiers M. C., Reeves D. S., Brumfitt W., Orskov F., Orskov I. R Factors in Escherichia coli in faeces after oral chemotherapy in general practice. Lancet. 1971 Feb 13;1(7694):312–315. doi: 10.1016/s0140-6736(71)91042-7. [DOI] [PubMed] [Google Scholar]
  2. KNOTHE H. [Intestinal flora and antibiotics with special reference to tetracycline]. Dtsch Med Wochenschr. 1963 Jul 26;88:1469–1477. doi: 10.1055/s-0028-1112252. [DOI] [PubMed] [Google Scholar]
  3. Linton K. B., Lee P. A., Richmond M. H., Gillespie W. A., Rowland A. J., Baker V. N. Antibiotic resistance and transmissible R-factors in the intestinal coliform flora of healthy adults and children in an urban and a rural community. J Hyg (Lond) 1972 Mar;70(1):99–104. doi: 10.1017/s0022172400022130. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. SEARS H. J., BROWNLEE I., UCHIYAMA J. K. Persistence of individual strains of Escherichia coli in the intestinal tract of man. J Bacteriol. 1950 Feb;59(2):293–301. doi: 10.1128/jb.59.2.293-301.1950. [DOI] [PMC free article] [PubMed] [Google Scholar]

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