Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1973 Oct;4(4):495–496. doi: 10.1128/aac.4.4.495

Immunosuppressive Effect of 6-Mercaptopurine and Mitomycin C

James A Majeski a,1, B Theodore Cole a
PMCID: PMC444582  PMID: 4598616

Abstract

6-Mercaptopurine and mitomycin C were used in combination drug therapy to produce a prolongation of skin allograft survival.

Full text

PDF
495

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BIEBER S., ELION G. B., HITCHINGS G. H., HOOPER D. C., NATHAN H. C. Suppression of the immune response by drugs in combination. Proc Soc Exp Biol Med. 1962 Nov;111:334–337. doi: 10.3181/00379727-111-27783. [DOI] [PubMed] [Google Scholar]
  2. Friedman E. A., Gelfand M., Bernheimer H. P. Synergism in immunosuppression. I. Effect of methylprednisolone, azathioprine, chlorambucil, and radiation on tetanus antitoxin production. Transplantation. 1971 May;11(5):479–486. [PubMed] [Google Scholar]
  3. IYER V. N., SZYBALSKI W. A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDS. Proc Natl Acad Sci U S A. 1963 Aug;50:355–362. doi: 10.1073/pnas.50.2.355. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. PHILIPS F. S., SCHWARTZ H. S., STERNBERG S. S. Pharmacology of mitomycin C. I. Toxicity and pathologic effects. Cancer Res. 1960 Oct;20:1354–1361. [PubMed] [Google Scholar]
  5. REICH E., SHATKIN A. J., TATUM E. L. Bacteriocidal action of mitomycin C. Biochim Biophys Acta. 1961 Oct 14;53:132–149. doi: 10.1016/0006-3002(61)90800-9. [DOI] [PubMed] [Google Scholar]
  6. SHATKIN A. J., REICH E., FRANKLIN R. M., TATUM E. L. Effect of mitomycin C on mammalian cells in culture. Biochim Biophys Acta. 1962 Mar 5;55:277–289. doi: 10.1016/0006-3002(62)90783-7. [DOI] [PubMed] [Google Scholar]
  7. ZUKOSKI C. F., CALLAWAY J. M., RHEA W. G., Jr PROLONGATION OF CANINE RENAL HOMOGRAFT SURVIVAL BY ANTIMETABOLITES. Transplantation. 1963 Jul;1:293–297. doi: 10.1097/00007890-196301030-00004. [DOI] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES