Abstract
Serum and biliary tract levels of gentamicin were determined in a large series of patients. In only 17.7% of subjects were therapeutic serum levels achieved, even though recommended doses of gentamicin were administered. Therapeutic bile gentamicin levels were reached in only some of the patients with therapeutic serum levels.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Pitt H. A., Roberts R. B., Johnson W. D., Jr Gentamicin levels in the human biliary tract. J Infect Dis. 1973 Mar;127(3):299–302. doi: 10.1093/infdis/127.3.299. [DOI] [PubMed] [Google Scholar]
- Riff L. J., Jackson G. G. Pharmacology of gentamicin in man. J Infect Dis. 1971 Dec;124 (Suppl):S98–105. doi: 10.1093/infdis/124.supplement_1.s98. [DOI] [PubMed] [Google Scholar]
- Sabath L. D., Casey J. I., Ruch P. A., Stumpf L. L., Finland M. Rapid microassay for circulating nephrotoxic antibiotics. Antimicrob Agents Chemother (Bethesda) 1970;10:83–90. doi: 10.1128/AAC.10.1.83. [DOI] [PubMed] [Google Scholar]
- Smithivas T., Hyams P. J., Rahal J. J., Jr Gentamicin and ampicillin in human bile. J Infect Dis. 1971 Dec;124 (Suppl):S106–S108. doi: 10.1093/infdis/124.supplement_1.s106. [DOI] [PubMed] [Google Scholar]
- Waitz J. A., Weinstein M. J. Recent microbiological studies with gentamicin. J Infect Dis. 1969 Apr-May;119(4):355–360. doi: 10.1093/infdis/119.4-5.355. [DOI] [PubMed] [Google Scholar]