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. 1973 Nov;4(5):569–573. doi: 10.1128/aac.4.5.569

Rapid Gentamicin Bioassay Using a Multiple-Antibiotic-Resistant Strain of Klebsiella pneumoniae

Marlys E Lund 1,2,3, Donna J Blazevic 1,2,3, John M Matsen 1,2,3
PMCID: PMC444597  PMID: 4598849

Abstract

A rapid bioassay for gentamicin levels in serum was developed by using a strain of Klebsiella pneumoniae that has multiple resistance to antibiotics. Assays were comparable when performed on either small or large petri plates, and results were available in 2 to 4 h. Studies showed an overall recovery of 97.6% for gentamicin alone or 104.5% in the presence of commonly used antibiotics. The procedure can be performed without the need to inactivate other antibiotics that may be present in the serum sample.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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