Figure 3 –

Leukotriene B₄ (LTB₄), leukotriene C₄ (LTC₄), and prostaglandin E₂ are secreted primarily from goblet cell-enriched culture. TB₄, LTC₄, or prostaglandin E₂ in supernatants of HBE cells grown for 5, 10, or 14 days with basal exposure to IL-13 (0, 2, 5, or 10 ng/mL). Data are presented as the mean ± SEM from four samples. A, LTB₄. B, LTC₄. Significant differences from control subjects (no IL-13) at each date are indicated by **P < .01, ***P < .001, and from d 0 are indicated by #P < .01. C, Prostaglandin E₂. Significant differences are indicated by #P < .05, ##P < .01, and ###P < .001, and from control subjects at each date are indicated by *P < .05, **P < .01, and ***P < .001. See Figure 1 legend for expansion of abbreviations.