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. 2014 Nov 27;147(6):1599–1609. doi: 10.1378/chest.14-0258

Figure 9 –

Figure 9 –

Inhibiting either cyclooxygenase or lipoxygenase decreases sPLA2 V-stimulated MUC5AC secretion from goblet cells. Secreted MUC5AC, LTB4, and LTC4 in apical supernatants of goblet cells apically stimulated for 60 min or 24 h to sPLA2 V with quercetin, indomethacin, or MK-886 (0.1, 1, or 10 μM). A, MUC5AC; 60 min. B, LTB4; 24 h. C, LTC4; 24 h. Data are presented as mean ± SEM from four samples. *P < .05, **P < .02, ***P < .01, or ****P < .001 to quercetin, indomethacin, or MK-886 vehicle (dimethyl sulfoxide). See Figure 1 and 3 legends for expansion of abbreviations.