Figure 1. Kaplan-Meier curves representing time from seizure onset to administration of the first AED (green), second AED (blue), and third AED (red).

Time axis is truncated at 100 minutes. As an illustration of the delays in antiepileptic drug (AED) administration, 40 minutes after seizure onset, approximately 60% of patients had received their first AED, approximately 45% of patients had received a second AED, and approximately 25% of patients had received their third AED.