Table 1.
Parameter | Wt | Grx2aMacLDLR−/− |
---|---|---|
Females | n=10 | n=9 |
Weight, g | 30.8 ± 1.4 | 28.1 ± 0.8 |
Plasma total cholesterol, mg/dl | 586 ± 130 | 670 ± 98 |
Triglycerides, mg/dl | 96 ± 20 | 106 ± 14 |
Males | n=5 | n=11 |
Weight, g | 44.3 ± 1.4 | 41.1 ± 1.4 |
Plasma total cholesterol, mg/dl | 1244 ± 205 | 938 ± 183 |
Triglycerides, mg/dl | 195 ± 44 | 238 ± 25 |
After 14 weeks of HFD-feeding of LDLR−/− (Wt) and transgenic Grx2aMacLDLR−/− mice (Grx2aMacLDLR−/−) was completed, mice were weighed and plasma was obtained after cardiac punctures. Total plasma cholesterol and triglycerides were determined as described under Material and Methods. Results are expressed as mean ± SE.