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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Bone. 2015 May 8;78:203–211. doi: 10.1016/j.bone.2015.05.005

Table I.

Cranial Bone Volume, Density and Mineral Content in untreated vs. treated TNAP−/− and TNAP+/+ Mice.

Bone
Volume
Fraction		 Bone
Mineral
Content
(mg)		 Bone
Mineral
Density
(mg/cc)		 Tissue
Mineral
Content
(mg)		 Tissue
Mineral
Density
(mg/cc)
TNAP−/− vehicle frontal 0.31 +/− .16# .007 +/− .002*# 441 +/− 67*# .003 +/− .002# 602 +/− 31*#
TNAP−/− asfotase-alfa frontal 0.23 +/− .10 .006 +/− .001 401 +/− 34 .002 +/− .001 580 +/− 26
TNAP+/+ frontal 0.25 +/− .15 .006 +/− .002 411 +/− 49 .002 +/− .002 569 +/− 28
TNAP−/− vehicle parietal 0.32 +/− .13 .007 +/− .001 432 +/− 39 .003 +/− .002 594 +/− 27*
TNAP−/− asfotase-alfa parietal 0.29 +/− .12 .006 +/− .001 415 +/− 42 .003 +/− .001 579 +/− 32
TNAP+/+ none parietal 0.37 +/− .12 .007 +/− .001 443 +/− 37 .003 +/− .002 579 +/− 27
*

Indicates statistical significance between genotypes.

#

indicates statistical significance between treatment groups.