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. 2015 May 19;2(5):555–566. doi: 10.18632/oncoscience.166

Table 1. Overview of the externally visible tumor phenotypes in animals injected at the 8-cell stage with 20 pg of apc TALEN mRNA in a single blastomere.

Animal-Dorsal Animal-Ventral Vegetal-Dorsal Vegetal-Ventral
5 weeks 9 weeks 18 weeks 5 weeks 9 weeks 18 weeks 5 weeks 8 weeks 18 weeks 5 weeks 8 weeks 18 weeks
n=14 n=7 n=4 n=19 n=10 n=5 n=18 n=14 n=7 n=18 n=7 n=1
Epidermoid cysts 21% 14% 0% 47% 30% 0% 0% 0% 0% 5% 14% 0%
Desmoid tumors 0% 0% 0% 0% 50% 0% 0% 71% 86% 0% 71% 100%
Limb tumors 0% 0% 0% 0% 0% 0% 0% 0% 0% 33% 57% 0%
Survival (beyond 5 weeks) 50% 29% 53% 26% 78% 39% 39% 6%