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. 2015 May 27;17(5):421–433. doi: 10.1016/j.neo.2015.04.003

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© 2015 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure S2 — Lung metastasis in C3(1)-Tag mice was not influenced by Mmp9 status. The lung metastatic burden was examined by histology in C3(1)-Tag;Mmp9^+/+ (n = 21), C3(1)-Tag;Mmp9^+/− (n = 19), and C3(1)-Tag;Mmp9^−/− (n = 14) mice at end stage. There were no significant differences in (A) total lung metastatic burden, (B) number of metastatic foci, nor (C) average size of metastatic foci when comparing C3(1)-Tag;Mmp9^+/+, C3(1)-Tag;Mmp9^+/−, and C3(1)-Tag;Mmp9^−/− mice (one-way ANOVA).