Table 5.

Medication Administration and Agency for Healthcare and Research Quality ICD-9 code Derived Patient Safety Indicator Events

Event			Participants taking both CNI and Statin
		Yes			No
		N		%	N		%	p-value
Myopathy	Yes	30		1	14		1	0.35
	No	2494		99	1572		99
			Participants taking both ACEI and AZA
		Yes			No
		N		%	N		%	p-value
Shock/Sepsis	Yes	19		5	297		8	0.04
	No	359		95	3435		92
			Participants taking Sulfonylurea or Metformin stratified by tertile of GFR
			Yes			No
			N	%		N	%		p value
Diabetic Ketoacidosis/Coma*
Low tertile GFR.........Yes			70	34.5		133	65.5		<.0001
.................................... No			207	18.5		915	81.5
Middle tertile GFR......Yes			70	32.9		171	15.4		<.0001
.................................... No			143	67.1		938	84.6
High tertile GFR........Yes			61	28.1		197	17.1		.0001
.................................... No			156	71.9		955	82.9
Hypoqlycemia**
Low tertile GFR.........Yes			6	3.0		32	2.8		0.83
.................................... No			197	97.0		1090	97.2
Middle tertile GFR ..Yes			10	4.7		13	1.2		0.002
.................................... No			203	95.3		1096	98.8
High tertile GFR..... ..Yes			8	3.7		18	1.6		0.052
.................................... No			209	96.3		1134	98.4

CNI – calcineurin inhibitor, AZA = azathioprine, ACEI = angiotensin-converting enzyme inhibitor GFR=estimated glomerular filtration rate.

^*p value = 0.34