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Annals of Oncology logoLink to Annals of Oncology
. 2015 Apr 22;26(5):1038–1039. doi: 10.1093/annonc/mdv140

A 3′-UTR KRAS-variant is associated with cisplatin resistance in patients with recurrent and/or metastatic head and neck squamous cell carcinoma

PMCID: PMC4481560  PMID: 25900677

Ann Oncol 2014; 25: 2230–2236 (doi: 10.1093/annonc/mdu367)

In the original manuscript, there was an error in Figure 1 panel E and F.

The orange line should indicate TG/GG-placebo and the pink line should indicate TG/GG-cetuximab in the survival plots. The figure has been corrected below.

Figure 1.

Figure 1.

Kaplan–Meier survival plots by KRAS-variant status (variant TG/GG versus non-variant TT). (A) Progression-free survival from HN0501 (phase II trial of docetaxel + bortezomib in R/M HNSCC patients); (B) overall survival from HN0501; (C) progression-free survival from E5397 (randomized phase III trial of cisplatin + placebo versus cisplatin + cetuximab in R/M HNSCC patients); (D) overall survival from E5397; (E) progression-free survival by KRAS-variant status (variant TG/GG versus non-variant TT) and E5397 treatment arms (cisplatin + placebo versus cisplatin + cetuximab); and (F) overall survival by KRAS-variant status (variant TG/GG versus non-variant TT) and E5397 treatment arms (cisplatin + placebo versus cisplatin + cetuximab).


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