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. 1994 Sep 27;91(20):9505–9508. doi: 10.1073/pnas.91.20.9505

Cerebrodiene: a brain lipid isolated from sleep-deprived cats.

R A Lerner 1, G Siuzdak 1, O Prospero-Garcia 1, S J Henriksen 1, D L Boger 1, B F Cravatt 1
PMCID: PMC44841  PMID: 7937797

Abstract

We report the isolation of a heretofore unrecognized brain lipid that is present in cerebrospinal fluid of sleep-deprived cats. The molecule appears to be a long-chain base structurally related to sphingosine and sphinganine in which a second unsaturated bond has been introduced. An increase in the degree of unsaturation of a key membrane component is expected to have important physiological consequences.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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