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(A) Pygo2 protein and mRNA expression pattern in human HCC cell lines. (B) Pygo2 protein level was dramatic decreased in 97H-shPygo2 cells. (C) Down-regulation of Pygo2 repressed MHCC-97H cell invasion and migration. (D) Pygo2 protein was increased in Huh7-overexpression Pygo2 cells. (E) Over-expression of Pygo2 promoted Huh7 cell invasion and migration. **P ≤ 0.01, ***P ≤ 0.001.
