Fig. 5.

Multimodal optogenetics configurations for experiments in freely moving animals: (a) representation of a mouse implanted with a fiber optic cannula and a chronic electrophysiogical electrode and the rotary joints enabling free movements of the animal; (b) image of a mouse implanted with a wireless optogenetic system (Figure modified from Ref. 110); (c) schematics of the layer composition of multifunctional, implantable optoelectronic device incorporating various elements that can be used for wireless optogenetics and electrophysiology (adapted from Ref. 117).