Table 1.
Currently known mechanisms by which the agent acts | ||||
---|---|---|---|---|
Agent | DCs | NK cells | γδ T cells | CD8+ T cells |
IL-2 | Unconfirmed | Telomerase activation121 Decrease apoptosis133 |
Reversal of anergy138 | Decrease apoptosis134 Reversal of anergy138,139 |
IL-7 | Unconfirmed | Decrease apoptosis133 | Unconfirmed | Telomerase activation125 Decrease apoptosis88 |
IL-21 | Induces Apoptosis107,108 | Telomerase activation122 | Unconfirmed | Unconfirmed |
IL-15 | Decrease apoptosis136 | Decrease apoptosis130,131 | Unconfirmed | Telomerase activation123–125 Decrease apoptosis132 |