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. Author manuscript; available in PMC: 2015 Jul 6.
Published in final edited form as: Biochemistry. 2015 Apr 29;54(18):2858–2873. doi: 10.1021/acs.biochem.5b00064

Table 1. Amino Acid Sequence of de novo Designed Peptidesa.

Peptide Sequence Reference
abcdefg abcdefg abcdefg abcdefg
CoilSer AC-E WEALEKK LAALESK LQALEKK LEALEHG -NH2 10
abcdefg abcdefg abcdef loop
MGSWAEFKQR LAAIKTR LQAL GGS 8
α3D EAELAAFEKE IAAFESE LQAY KGKG
NPEVEALRKE AAAIRDE LQAYRHN 23
MGSWAEFKQR LAAIKTR CQAL GGS
α3DIV EAECAAFEKE IAAFESE LQAY KGKG
NPEVEALRKE AAAIRDE CQAYRHN
α3DH3 MGSWAEFKQR LAAIKTR HQAL GGS 56
α3DH3 EAEHAAFEKE IAAFESE LQAY KGKG
NPEVEALRKE AAAIRDE HQAYRVN GSGA
a

The sequences are prepared in heptads. Residues that are underlined and bolded were changed from the previous design.