Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The cavity available to the cis anionic chromophore in the M159T structure (yellow surface) is enlarged relative to Dronpa (white surface) as a result of the reduced side chain as well as a 1.4 Å ‘outward retraction’ of the side chain (Dronpa-M159T: yellow scheme / Dronpa: green scheme 2Z1O 10). The cavity volume shown does not include crystal waters. 2Fo-Fc electron density is contoured at the 2.0 sigma level for chromophore and residues 156-171 for the Dronpa-M159T structure.
