Table 1. Relationship between ERp19 expression level and clinicopathological variables in 90 GC patients.
Clinicopathological variable | No. of patients | ERp19 staining | P value | |
---|---|---|---|---|
Weak | Strong | |||
Normal tissue | 90 | 56 | 34 | 0.007* |
Gastric carcinoma | 90 | 38 | 52 | |
Age (years) | 0.423 | |||
<60 | 29 | 14 | 15 | |
≽60 | 61 | 24 | 37 | |
Gender | 0.728 | |||
Male | 67 | 29 | 38 | |
Female | 23 | 9 | 14 | |
Tumor size (cm) | 0.041* | |||
≼5 | 34 | 19 | 15 | |
>5 | 56 | 19 | 37 | |
Histological grade | 0.584 | |||
Well, Moderately | 24 | 9 | 15 | |
Poorly, undifferentiated | 66 | 29 | 37 | |
Lauren's classification | 0.108 | |||
Intestinal-type | 56 | 20 | 36 | |
Diffuse-type | 34 | 18 | 16 | |
Lymph node involvement | 0.034* | |||
Absence | 25 | 15 | 10 | |
Presence | 65 | 23 | 42 | |
TNM stage | 0.433 | |||
I+II | 36 | 17 | 19 | |
III+IV | 54 | 21 | 33 |
Immunohistochemistry (IHC) scores were calculated by multiplying the percentage of positive cells (0 is <5% positive cells, 1 is 5%-25% positive cells, 2 is 25%-50% positive cells, 3 is 50%-75% positive cells and 4 is >75% positive cells) by stain intensity (0 is no staining, 1 is weak staining, 2 is moderate staining and 3 is strong staining) in five different high power fields for each section. The IHC score of 0-3 was defined as weak expression and 4-12 as strong expression.