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. 2015 Mar 20;6(11):9341–9354. doi: 10.18632/oncotarget.3322

Figure 3. sNEDD4 promotes tumor cell invasion in vitro.

Figure 3

NEDD4 and sNEDD4 protein levels of cells were determined using Western blot (A–C upper panel). The invasive ability of cells was determined with the Transwell invasion assay (A–C, middle and lower panel). P1 and P2, control stable SK cell lines; sN1 and sN2, stable sNEDD4-overexpressing SK cells; Vec, empty vector control; FL, full-length NEDD4; S, sNEDD4; CDS, NEDD4 shRNA target to coding region; 3′UTR, NEDD4 shRNA target to the 3′-untranslated regions; *P < 0.05; **P < 0.01; ***P < 0.001.