Table 1. Tumorigenic potential of indicated MEFs in vivo.
E1A/Ras Hipk2+/+ | E1A/Ras Hipk2−/− | |||||||
---|---|---|---|---|---|---|---|---|
Injected cell number | 2×106 | 5×106 | 1×107 | 2×107 | 1×103 | 1×104 | 5×105 | 2×106 |
Tumor incidence | 0/5 | 0/5 | 0/5 | 3/3 | 0/3 | 1/3 | 3/5 | 5/5 |
Tumor appearance | n.a. | n.a. | n.a. | 7 | n.a. | 13 | 5 | 5 |
Tumor incidence is reported as tumor bearing mice/number of injected mice. Tumor appearance is reported as days post injection. n.a., not applicable.