Usp1 |
WDR48 (Uaf-1) |
DNA damage response, Fanconi anaemia pathway, homologous recombination, cellular differentiation and Akt signalling |
Usp3 |
WDTC1 |
DNA repair and cell cycle progression |
Usp7 |
BUB3, WDR21A, RAE1 |
Gene expression, protein stability, cell cycle progression and proliferation |
Usp12 |
WDR20, WDR26, WDR48, WDR77, DMWD |
Transcription, Notch signalling and Akt signalling |
Usp22 |
TAF5L |
Gene expression, protein stability, proliferation and cell cycle progression |
Usp42 |
WDR18 |
Transcription, stress response and cell-cycle progression. When fused to RUNX1 it is involved in pathogenesis of acute leukaemia |
Usp44 |
TBL2 |
DNA repair, cell cycle progression and differentiation |
Usp46 |
WDR20, WDR26, WDR48, WDR77, DMWD |
Transcription, nervous system development and Akt signalling |
Usp49 |
COPA |
Gene expression and pre-mRNA processing |
Usp50 |
PRPF4 |
Cell cycle progression |