Table 3.
13 weeks HFD Post-surgery | ||||
---|---|---|---|---|
Chow Sham (n = 10) | Chow IngX (n = 10) | HFD Sham (n= 10) | HFD IngX (n = 10) | |
Food Intake (kcal/g) | 886.0 ± 28.6a | 905.9 ± 15.9a | 99.4 ± 22.8b | 984.0 ± 19.40b |
Body Weight (g) | 31.75 ± 1.08a | 32.50 ± 1.05a | 41.11 ± 1.17b | 41.19 ± 0.69b |
Inguinal Pad (g) | 0.58 ± 0.05a | 0.12 ± 0.02b | 1.52 ± 0.09c | 0.38 ± 0.03d |
Brown Interscapular (g) | 0.23 ± 0.02a | 0.23 ± 0.03a | 0.44 ± 0.03b | 0.45 ± 0.02b |
Epididymal (g) | 0.82 ± 0.10a | 0.90 ± 0.12a | 1.93 ± 0.12b | 2.03 ± 0.08b |
Perirenal (g) | 0.40 ± 0.05a | 0.38 ± 0.07a | 0.98 ± 0.06b | 1.05 ± 0.05b |
Visceral (g) | 0.36 ± 0.04a | 0.37 ± 0.05a | 0.82 ± 0.07b | 1.01 ± 0.10b |
Pre-Glucose Intolerant | ||||
Chow Sham (n = 10) | HFD Sham (n = 10) | HFD IngX (n = 10) | ||
Food Intake (Kcal/g) | 274.8 ± 4.24a | 323 ± 11.54b | 324.8 ± 6.53b | |
Body Weight (g) | 32.91 ± 0.99a | 37.20 ± 1.71b | 37.00 ± 0.66b | |
Inguinal Pad (g) | 0.52 ± 0.07a | 1.02 ± 0.14b | 0.27 ± 0.05c | |
Brown Interscapular (g) | 0.23 ± 0.02a | 0.39 ± 0.05b | 0.39 ± 0.03b | |
Epididymal (g) | 0.78 ± 0.11a | 1.50 ± 0.20b | 1.60 ± 0.15b | |
Perirenal (g) | 0.41 ± 0.06a | 0.69 ± 0.08b | 0.80 ± 0.09b | |
Visceral (g) | 0.42 ± 0.07 | 0.59 ± 0.09 | 0.61 ± 0.06 |
13 week HFS post-surgery—Cumulative energy intake, adiposity, and body mass of HFD mice were significantly greater than Chow. Recovered inguinal adipose mass was significantly reduced in IngX mice compared to Sham, but IngX did not result in significant changes to the mass of non-excised adipose depots. Pre-glucose intolerant—adiposity and body mass and 5 week post-surgery food intake were significantly higher in HFD groups compared with Chow. In HFD mice, IngX significantly decreased inguinal depot mass compared with Sham, but did not result in changes to non-excised depot mass. (Unlike letters indicate significance; P ≤ 0.05)