Table 1. Comparison of Peloruside A and Paclitaxel for inhibition of different biological activities.
Biological Activity | Paclitaxel (nM) (IC50) | Peloruside A (nM) (IC50) |
---|---|---|
Cell division | 8.0 | 20.0 |
Cell migration | 0.65 | 0.10 |
Microtubule dynamicity | 0.50 | 0.10 |
Tube formation | 0.50 | 0.10 |