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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Neuron. 2015 Jul 1;87(1):28–46. doi: 10.1016/j.neuron.2015.06.012

Figure 5.

Figure 5

Representative functions of structured non-coding RNAs in cells. A) Schematic of a triplex formed between DNA and lncRNA that allosterically recruits gene-regulating proteins. B) Simplified representation of SRP RNA’s role in targeting membrane proteins to the endoplasmic reticulum (ER) for their proper folding. C) Schematic of co-transcriptional cleavage element regulating transcription termination of the β-globin gene. CoTC, co-transcriptional cleavage element; ER, endoplasmic reticulum; RNA Pol II, RNA polymerase II; SRP, signal recognition particle