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. 2015 Aug;21(8):1511–1518. doi: 10.1261/rna.051474.115

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© 2015 Li et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 4. — m⁶A interferes with A–U or A–T pairing. (A) Pie chart indicating genic location of significant probes (SPs). (B) Bar plots show specific enrichment of SPs on long (>300 nt) versus short (≤300 nt) exons (P < 2.79 × 10⁻⁷; Fisher's exact test). (C) Bar plots showing enrichment of the RRACH motif within 206 SPs and remaining probes (P < 6.11 × 10⁻⁵; Fisher's exact test). (D) GO analysis of 64 protein-coding genes containing SPs (P < 0.05). The number of gene hits in a GO category is indicated within the bars. (E). Bar plots showing that meRIP-seq peaks containing SPs exhibit significantly decreased binding to AGO2 than do those from remaining probes. Fisher's exact test, P < 0.0012.