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. 2015 May 11;156(8):2905–2917. doi: 10.1210/en.2015-1074

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This article has been published under the terms of the Creative Commons Attribution License (CC-BY; https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Copyright for this article is retained by the author(s).

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Figure 1. — Azin1, Odc, and Az1 mRNA expression in rat SON and PVN in response to hyperosmotic stress. The expression of Azin1, Odc, and Az1 were examined in the SON and PVN in chronic and acute hyperosmotic conditions and after water repletion. A, Relative mRNA expression of Azin1, Odc, and Az1 was investigated by qPCR in SON and PVN of EH, DH (1 and 3 d), and SL (1 and 7 d) rats. B, Relative mRNA of Azin1 and Odc in rat SON and PVN after water repletion for 1 day after 1-day DH and 1-day SL compared with EH controls. C, Changes in Azin1, Odc, Az1, and AVP mRNA expression and hnAVP expression after a single ip injection of 1.5 mL per 100 g body weight 1.5 M NaCl over 240 minutes of the experimental period compared with controls. Values are means ± SEM of n = 5–6 animals per group. *, P < .05; **, P < .01; ***, P < .001.