Figure 3.

Effect of l-arginine or l-citrulline supplementation on plasma amino acid concentrations in control and arginase treated mice. (A) Plasma arginine concentrations during basal and arginase-treated conditions with or without citrulline or arginine; (B) plasma citrulline concentration in all treated groups; (C) ornithine concentrations during basal and arginase-treated conditions; (D) lysine concentrations in plasma were measured with HPLC. Plasma concentrations are displayed as μmol/L. Significance: ^a p < 0.05 vs. control; ^b p < 0.05 vs. arginine; ^c p < 0.05 vs. arginine + arginase; ^d p < 0.05 vs. citrulline + arginase.