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. 2015 Jun 29;7(7):5217–5238. doi: 10.3390/nu7075217

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Effect of l-arginine or l-citrulline supplementation on jejunal tissue amino acid concentrations in control and arginase-treated mice. Jejunal tissue concentrations during basal and arginase-treated conditions of (A) arginine, (B) citrulline, (C) ornithine and (D) lysine were measured with High Performance Liquid Chromatography (HPLC). Tissue concentrations are displayed as nmol/g wet tissue). Significance: ^a p < 0.05 vs. control; ^b p < 0.05 vs. arginine; ^c p < 0.05 vs. arginine + arginase; ^d p < 0.05 vs. citrulline + arginase.