Skip to main content
. 2015 Jul 17;7(7):3910–3936. doi: 10.3390/v7072804

Figure 2.

Figure 2

Steps of the HIV-1 replication cycle that can be targeted by gene therapy. The HIV-1 replication steps that can be targeted by gene therapy are shown: (1) HIV-1 binding to cell membrane; (2) HIV-1 entry into the cell; (3) reverse transcription; (4) transport of the HIV-1 proviral genome into the nucleus; (5) integration of the viral genome into the cellular DNA; (6) transcription of the HIV-1 proviral genome; (7) translation of the viral messenger RNA (mRNA) into new viral proteins; (8) virion assembly inside the cell; and (9) maturation of the immature virion into a completely infectious particle.