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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Xenotransplantation. 2015 Jun 1;22(4):295–301. doi: 10.1111/xen.12172

Fig. 4.

Fig. 4

IL-4 and IL-13 induced protection against killing of ECs by melittin but did not prevent melittin-induced loss of permeability control. ECs were incubated with medium alone or with IL-4 or IL-13 at 10 ng/mL for 48 h, and then tested for sensitivity to killing by 2.5 μM melittin for 2 h. EC killing was determined by neutral red uptake and permeability was measured by LDH release. Results are means ± S.E.M. of 3 experiments that were performed in triplicate. LDH release vs. killing for IL-4- and IL-13-treated, p < 0.001.