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. 2015 Jul 27;2015:bcr2015211433. doi: 10.1136/bcr-2015-211433

Raymond syndrome and conjugate gaze palsy from a paramedian pontine infarct

Bik Ling Man 1, Yat Pang Fu 2
PMCID: PMC4521556  PMID: 26215110

Description

A 65-year-old man with a history of hypertension, diabetes mellitus and hyperlipidaemia, was admitted for sudden-onset binocular diplopia and right-sided weakness. Physical examination showed left abducens nerve palsy and impaired left horizontal conjugate gaze (video 1). Saccades and smooth pursuit were impaired. The horizontal vestibulo-ocular reflex was impaired (video 2). Pupillary and levator function was normal. The patient had right-sided central paresis of the lower part of the face and limbs (Medical Research Council grading 0/5). MRI of the brain revealed a paramedian left pontine infarct (figure 1). His condition improved significantly after treatment with aspirin and rehabilitation therapy.

Figure 1.

Figure 1

Diffusion-weighted MRI showing a paramedian left pontine infarct (arrow).

Video 1.

Download video file (17MB, mp4)
DOI: 10.1136/bcr-2015-211433.video01

Left abducens nerve palsy and impaired left horizontal conjugate gaze.

Video 2.

Download video file (15.6MB, mp4)
DOI: 10.1136/bcr-2015-211433.video02

Impairment of the horizontal vestibulo-ocular reflex.

Raymond syndrome with conjugate gaze palsy is rare. Raymond syndrome is characterised by ipsilateral abducens nerve palsy with contralateral limbs and central facial paresis. It is caused by lesions of medial caudal pons damaging the abducens nerve and the non-decussated corticofacial and pyramidal fibres.1 Some patients have had lesions sparing the corticofacial fibres without having contralateral facial paresis.2 Conjugate gaze palsy is caused by lesions damage the abducens nucleus resulting in complete ipsilateral eye movement paralysis.3

Learning points.

  • Raymond syndrome with conjugate gaze palsy is rare.

  • Raymond syndrome is characterised by ipsilateral abducens nerve palsy with contralateral limbs and central facial paresis. It is caused by lesions of medial caudal pons damaging the abducens nerve, and the non-decussated corticofacial and pyramidal fibres.

  • Conjugate gaze palsy is caused by lesions damaging the abducens nucleus resulting in complete ipsilateral eye movement paralysis.

Footnotes

Competing interests: None declared.

Patient consent: Obtained.

Provenance and peer review: Not commissioned; externally peer reviewed.

References


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