. Author manuscript; available in PMC: 2015 Aug 8.

Published in final edited form as: Biochemistry. 2010 Mar 16;49(10):2150–2158. doi: 10.1021/bi9021507

Table 2.

NO and Cyanide Binding to Ferric Heme Proteins^a

	NO (Fe^III)			CN (Fe^III)
	k _on	k _off	K _D	k _on	k _off	K _D	ref
MPO	1070	11	10	1300	0.56	0.43	28, 101
LPO	3000	nd	nd	1100	20	18	28, 102
EPO	1350	65	48	nd	nd	nd	28
HRP	190	75	400	98	0.28	2.9	103, 104
CcP	nd	nd	nd	110	0.9	8.2	105
Mb	190	14	74	0.17	3.8 × 10⁻⁴	2.2	106, 107

Data cited are the association (k_on, ×10³ M⁻¹ s⁻¹) and dissociation (k_off, s⁻¹) rate constants, together with the corresponding dissociation constant (K_D, μM); nd, not determined.