TABLE 2.
Adjusted Outcomes
| Narrow-Spectrum (n = 256) | Broad-Spectrum (n = 236) | P | |
|---|---|---|---|
| LOS, h | 43 (39–46) | 52.3 (48–57) | .04 |
| Duration of supplemental oxygen, h | 15.6 (12–20) | 21.8 (17–29) | .18 |
| Duration of fever, h | 6.5 (5–9) | 9.1 (7–12) | .23 |
| Standardized cost per day, $ | 2209 (2088–2338) | 2160 (2042–2286) | .62 |
| Standardized pharmacy cost per day, $ | 170 (153–188) | 188 (170–208) | .26 |
| Readmission within 7 daysa | Reference | 5.1 (0.3–83.6) | .25 |
Data are least-squares means (95% CI) unless otherwise indicated and were adjusted for age, gender, race, government insurance, concurrent diagnosis of asthma or reactive airway disease, previous antibiotic therapy, atypical antibiotic therapy, presence of effusion on chest radiograph, diagnosis of viral lower respiratory tract infection, admission to the ICU, blood culture utilization, presence of a positive blood culture, baseline hospital rates for cephalosporin use, tachypnea, fever, and abnormal WBC.
a
Data are adjusted odds ratios (95% CI) for broad-spectrum/penicillin therapy.