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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: ChemMedChem. 2014 Sep 10;9(12):2633–2637. doi: 10.1002/cmdc.201402333

Figure 5.

Figure 5

Assessing the cytotoxicity of PLD2 inhibitor 3 versus ML395 (6l). A) microscopic image of A549 cells treated with ML395 (6l) showing no cellular toxicity after 24 hours, bar = 50 μm. B) microscopic image of A549 cells treated with 3 showing significant cellular toxicity after 24 hours, bar = 50 μm. C) A dose response of 3 and ML395 in a 24 hour cytotoxicity in A549 cells. PLD2 inhibitor 3 displays significant toxicity at concentrations above 10 μM, whereas ML395 is comparable to DMSO at concentrations up to 50 μM.