Table 1A. Accuracy of the combination model in diagnosing Ta/T1 bladder cancer.
| Biomarkers | AUC | Sensitivity % | Specificity % | PPV % | NPV % | Overall accuracy % | |
|---|---|---|---|---|---|---|---|
| ELISA | All five biomarkers in combination | 0.92 | 79.2 | 100 | 100 | 66.7 | 85.3 |
| Western blot | All five biomarkers in combination | 0.98 | 93.9 | 96.7 | 98.4 | 87.9 | 94.8 |
| Three biomarkers (Coronin-1A, Apolipoprotein A4, DJ-1) in combination | 0.97 | 92.4 | 93.3 | 96.8 | 84.8 | 92.7 | |
| Four biomarkers (Coronin-1A, Apolipoprotein A4, Semanogelin-2, DJ-1) in combination | 0.98 | 90.9 | 96.7 | 98.4 | 82.9 | 92.7 | |
Abbreviations: AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value.