Correction: Mechanism of Inhibition of the Human Sirtuin Enzyme SIRT3 by Nicotinamide: Computational and Experimental Studies

The authors would like to provide the expressions for K₁,K₂,K₃, K_m,NAD+ and v_max for Equation 3, which should have been included as a supplementary file with the article.

The expressions for K₁,K₂,K₃,K_m,NAD+ and v_max are provided in S1 File in this Correction.

For sirtuins, k_cat<< k_j, j ≠ cat does not imply K_{m, NAD+} ≈ K_{d, NAD+}; see S1 File.

Supporting Information

S1 File. Initial rate model for sirtuin deacetylation kinetics.

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