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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neuropharmacology. 2015 May 19;97:67–74. doi: 10.1016/j.neuropharm.2015.05.009

Figure 1.

Figure 1

Effect of CEF treatment on ethanol intake and ethanol preference in male P rats. P rats had free access to ethanol (15% and 30%, concurrently) and/or water for five weeks. P rats were treated with CEF (100 mg/kg/day, i.p.) or saline (i.p.) for five consecutive days during week six. Ethanol and water intake were measured during the last two weeks and served as baseline intake. A. CEF treatment significantly reduced ethanol intake in EtOH-CEF group during treatment period (day 1 through day 5) compared to the EtOH-Sal group (#, p<0.0001). B. CEF treatment significantly decreased ethanol preference in EtOH-CEF group during treatment period (day 1 through day 5) compared to the EtOH-Sal group (&, p<0.001; #, p<0.0001). All data are expressed as mean ± SEM. n=8/ group. EtOH, ethanol; Sal, Saline; CEF, ceftriaxone.