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. 1988 Jul;7(7):2185–2189. doi: 10.1002/j.1460-2075.1988.tb03057.x

Excision of the Drosophila transposable element mariner: identification and characterization of the Mos factor.

M M Medhora 1, A H MacPeek 1, D L Hartl 1
PMCID: PMC454541  PMID: 2843360

Abstract

Genetic and molecular evidence presented in this paper demonstrate that the Mos factor for inherited mosaicism is a special copy of the transposable element mariner. Mosaicism observed in the presence of the Mos (Mosaic) factor results from a high frequency of excision of the mariner element from an insertion site near the white-eye gene in Drosophila mauritiana. The Mos factor promotes the excision of mariner elements from genomic insertion sites other than the site in wpch, and it also promotes its own loss from the genome. Putative transpositions of Mos to new genomic sites have also been observed. A copy of mariner present at a particular site in a Mos strain has been shown to be missing in derived strains in which the Mos factor has been lost, and in strains with putative transpositions. We propose that this copy of mariner is identical to the Mos factor.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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