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. 2015 May 22;6(16):13899–13913. doi: 10.18632/oncotarget.4224

Figure 2. Schematic overview of different GANT61 target sites.

Figure 2

Inhibition of the GLI transcription factors with GANT61 targets many of the “classical hallmarks of cancer”, such as cell viability, proliferation, apoptosis, DNA damage repair, epithelial-mesenchymal transition (EMT), autophagy, cancer stem cells and immune response.