Table 3. Base-case and univariate scenario analysis (2013 US$).
ICER/Case | ICER/Death | ICER/DALY | Break-even price | |
---|---|---|---|---|
Societal perspective | ||||
| ||||
Base-case | 6,252 | 26,476 | 1,231 | 0.69 |
Life expectancy of a sequelae case = 30 years | 6,338 | 26,840 | 1,271 | 0.67 |
Discount rate=0% for cost and effectiveness | 2,235 | 8,240 | 385 | 1.81 |
Discount rate=5% for cost | 5,963 | 25,253 | 1,175 | 0.78 |
Meningitis incidence = 34/100,000 child-year | 4,282 | 17,322 | 803 | 0.84 |
Clinical pneumonia incidence = 0.35/child-year | 1,465 | 10,119 | 490 | 0.91 |
Productivity loss from death included | 5,688 | 24,084 | 1,120 | 0.86 |
| ||||
Governmental perspective | ||||
| ||||
Base-case | 6,954 | 29,449 | 1,370 | 0.48 |
Life expectancy of a sequelae case = 30 years | 6,953 | 29,444 | 1,394 | 0.48 |
Discount rate=0% for cost and effectiveness | 5,350 | 19,720 | 923 | 0.72 |
Discount rate=5% for cost | 6,883 | 29,147 | 1,356 | 0.5 |
Meningitis incidence=34/100000 child-year | 5,037 | 20,381 | 945 | 0.54 |
Clinical pneumonia incidence=0.35/child-year | 1,720 | 11,883 | 576 | 0.61 |
Note: ICER, incremental cost-effectiveness ratio; DALY, disability-adjusted life year.