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. Author manuscript; available in PMC: 2016 Aug 26.
Published in final edited form as: Vaccine. 2015 Jun 1;33(36):4639–4646. doi: 10.1016/j.vaccine.2015.05.050

Table 3. Base-case and univariate scenario analysis (2013 US$).

ICER/Case ICER/Death ICER/DALY Break-even price
Societal perspective

Base-case 6,252 26,476 1,231 0.69
Life expectancy of a sequelae case = 30 years 6,338 26,840 1,271 0.67
Discount rate=0% for cost and effectiveness 2,235 8,240 385 1.81
Discount rate=5% for cost 5,963 25,253 1,175 0.78
Meningitis incidence = 34/100,000 child-year 4,282 17,322 803 0.84
Clinical pneumonia incidence = 0.35/child-year 1,465 10,119 490 0.91
Productivity loss from death included 5,688 24,084 1,120 0.86

Governmental perspective

Base-case 6,954 29,449 1,370 0.48
Life expectancy of a sequelae case = 30 years 6,953 29,444 1,394 0.48
Discount rate=0% for cost and effectiveness 5,350 19,720 923 0.72
Discount rate=5% for cost 6,883 29,147 1,356 0.5
Meningitis incidence=34/100000 child-year 5,037 20,381 945 0.54
Clinical pneumonia incidence=0.35/child-year 1,720 11,883 576 0.61

Note: ICER, incremental cost-effectiveness ratio; DALY, disability-adjusted life year.