Table 1.
All 14 QA methods with the details
| Methods | Type | Features |
|---|---|---|
| MULTICOM-NOVEL | Single | Structural, physical, chemical features |
| OPUS-PSP | S | Contact potentials based on side chain functional groups |
| ProQ2 | S | Structural features |
| RWplus | S | Side-chain orientation dependent potential |
| ModelEvaluator | S | Structural features, contacts |
| Modelcheck2 | S | Structural features, contacts, disorder, conservation |
| RF_CB_SRS | S | Distance dependent statistical potential |
| SELECTpro | S | Energy-based (h-bond, angle, electrostatics, vdw) |
| Dope | S | Statistical potential |
| DFIRE2 | S | Energy-based potential |
| ModFOLDclust2 | Multi | Pairwise model similarity (geometry) |
| APOLLO | M | Pairwise model similarity |
| Pcons | M | Pairwise model similarity |
| QApro | M+S | Weighted pairwise model similarity |
| MULTICOM (human) | Consensus | Average ranking |
The highlighted methods are built in house. S: single-model method; M: multi-model method.