Tx Protocol 2: 5 weekly RW+1018 ISS treatments were followed by 4 weekly RW exposures, final challenge of pulsed DCs (RWpDCs), DCs, RW or saline. (A) Th2 cytokines, eosinophils and genes, and (B) Th1 genes (mean +/− SEM, 8 mice/group). *P<0.05, **P <0.01, ***P<0.001, ****P<0.0001, compared to corresponding RW treatment group. Data representative of 2 experiments.