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. 2015 May 31;2(8):985–1000. doi: 10.1016/j.ebiom.2015.05.023

Panel 1.

List of interventions reviewed.

Pre pregnancy interventions
 Family planning
 Prevention and management of sexually transmitted infections including HIV
 Folic acid fortification and/or supplementation
Pregnancy interventions
 Antenatal care
 Iron and folic acid supplementation during pregnancy
 Tetanus immunization in pregnancy
 Prophylactic antimalarial and insecticide treated bednets for preventing malaria in pregnancy
 Interventions for smoking cessation during pregnancy
 Screening and treatment of syphilis
 Prevention and management of HIV and prevention of mother to child transmission in pregnancy
 Calcium supplementation in pregnancy
 Low-dose aspirin for the prevention of pre-eclampsia
 Use of antihypertensive drugs for treating severe hypertension in pregnancy
 Prevention and treatment of eclampsia
 Reduce mal presentation at term using external cephalic version (> 36 weeks)
 Induction of labour for management of premature rupture of membranes at term.
 Antibiotics for management of preterm rupture of membranes
Childbirth interventions
 Corticosteroids for preventing neonatal respiratory distress syndrome
 Management of unintended pregnancy
 Social support during childbirth
 Prophylactic antibiotic for caesarean-section
 Prevention of postpartum haemorrhage: prophylactic uterotonic to prevent postpartum haemorrhage
 Active management of third stage of labour to prevent postpartum haemorrhage
 Induction of labour for prolonged pregnancy
 C-section for absolute maternal indication (e.g. obstructed labour and central placenta previa)
 Management of post-partum haemorrhage e.g. uterine massage
 Uterotonics
Postpartum interventions
 Advice and provision of family planning
 Prevent, measure and treat maternal anaemia
 Detection and management of postpartum sepsis
 Screening and initiation or continuation of ARV therapy for HIV
Neonatal interventions
 Promotion and provision of thermal care for all newborns to prevent hypothermia
 Promotion and support for early initiation and exclusive breastfeeding (within the first hour)
 Promotion and provision of hygienic cord and skin care
 Neonatal resuscitation with bag and mask for babies who do not breath at birth
 Newborn immunization
 Presumptive antibiotic therapy for the newborns at risk of bacterial infection
 Case management of neonatal sepsis, meningitis and pneumonia
 Kangaroo mother care for low birth babies
 Extra support for feeding the small and preterm baby
 Prophylactic and therapeutic use of surfactant to prevent respiratory distress syndrome in pre-term babies
 Continuous positive airway pressure (CPAP) to manage pre-term babies with respiratory distress syndrome
 Management of newborns with jaundice
Infant and child health interventions
 Promotion and support for exclusive breastfeeding for 6 months
 Continued breastfeeding up to 2 years and beyond
 Appropriate complementary feeding starting at 6 months
 Provision and promotion of use of insecticide treated bed nets for children
 Case management of childhood malaria
 Comprehensive care of children infected or exposed to HIV infection
 Promote and provide routine immunization plus H. Influenza, meningococcal, pneumococcal, and rotavirus vaccines
 Vitamin A supplementation from 6 months of age in Vitamin A deficient populations
 Management of severe acute malnutrition
 Case management of childhood pneumonia
 Vitamin A as part of treatment for measles-associated pneumonia for children above 6 months
 Vitamin A as part of treatment for non-measles-associated pneumonia for children above 6 months
 Case management of diarrhoea: Acute watery diarrhoea
 Dysentery
Cross cutting intervention
 Home visits across the continuum of care women's groups