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The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 2015 Aug 3;125(8):3304. doi: 10.1172/JCI83542

Kidney growth and hypertrophy: the role of mTOR and vesicle trafficking

Qais Al-Awqati
PMCID: PMC4563773  PMID: 26237046

Original citation: J Clin Invest. 2015;125(6):2267–2270. doi:10.1172/JCI81508.

Citation for this corrigendum: J Clin Invest. 2015;125(8):3304. doi:10.1172/JCI83542.

Two sentences were incorrect in the original manuscript. The first appeared in the section titled “Increased amino acid delivery causes compensatory hypertrophy.” The second appeared in the legend for Figure 1. The correct two sentences are below.

Once the mTORC1-containing complex is recruited to the lysosome, it encounters RHEB, whose inhibition activates it.

mTORC1 is recruited into a large protein complex on the lysosome surface composed of RAG GTPase, Ragulator, V-ATPase, and the amino acid transporter SLC38A9, allowing mTORC1 to be activated via inhibition of RHEB.

The author regrets the errors.

Footnotes

See the related article beginning on page 2267.


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