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Diagram of dual microarray element strategy. (a) Template DNA hybridizes with the bound surface promoter DNA on the generator element. (b) Surface transcription occurs on the generator element. (c) After diffusing to the detector element, surface transcribed RNAs get captured by hybridizing with the surface detector DNA. (d) SPRI sensing determines the quantity of DNA from the measured sum of transcripts hybridized with DNA-decorated AuNPs.
