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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Hypertension. 2015 Aug 17;66(4):793–799. doi: 10.1161/HYPERTENSIONAHA.115.05645

Figure 1.

Figure 1

Effect of anti-miR transfections in HMVEC-D on the abundance of mRNAs encoded by hypertension risk genes identified by human GWAS. HMVEC-D were transfected with the indicated LNA anti-miR or scrambled LNA anti-miR (10 nM) for 48 hours. mRNA abundance for predicted targets genes was measured by real-time RT-PCR and expressed as % change relative to cells treated with scrambled anti-miR on the same qPCR plate. ADM, adrenomedullin; ATP2B1, plasma membrane calcium-transporting ATPase 1; FGF5, fibroblast growth factor 5; GOSR2, Golgi SNAP receptor complex member 2; JAG1, jagged 1; PLECKHA7, pleckstrin homology domain containing, family A member 7; SH2B3, SH2B adapter protein 3; TBX3, T-box 3; TBX5, T-Box 5. N=3–9, *, P<0.05 vs. scrambled anti-miR.