The authors wish to make the following corrections to this paper [1]:
We have found eight inadvertent errors in our paper published in Mar. Drugs [1].
On page 1327, Line 6 and column 9 of Table 2, “18:3Δ6,12,15” should be “18:3Δ6,9,12”. Line 8 and column 8 of Table 2, “20:4Δ5,8,11,14,17” should be “20:4Δ8,11,14,17”. Line 9 and column 7, “Δ5/cis” should be “Δ4/cis”. Therefore replace this incorrect table:
Table 2.
Fatty acid desaturases of Phaeodactylum tricornutum—Characterized or predicted localization and substrate specificity. (*) functionally characterized; (?) based on predictions.
| Name | Gene ID | Subcellular Localization | Main Substrate | Main Product | ||||
|---|---|---|---|---|---|---|---|---|
| Acyl Linked to: | Carbon Number | Presence of Double Bonds | Position and Configuration of the Introduced Double Bond | Overall Structure | Overall Structure | |||
| PAD/SAD | Phatraft_9316 | Chloroplast stroma | ACP | 16 and 18 | 0 | Δ9/cis | 16:0-ACP | 16:1Δ9-ACP |
| ADS | Phatr_28797 | Endomembrane system | CoA | 18? | 0 | Δ9/cis? | 18:0-CoA? | 18:1Δ9-CoA? |
| FAD2 (*) | Phatr_25769 | ER | Phospholipid/ Betaine lipid? |
18 | 1 | Δ12 (or ω6)/cis | 18:1Δ9-PL (-BL?) | 18:2Δ9,12-PL (-BL?) |
| ERΔ6FAD (*) | Phatr_2948 | ER | Phospholipid/ Betaine lipid? |
18 | 2 | Δ6/cis | 18:2Δ9,12-PL (-BL?) | 18:3Δ6,12,15-PL (-BL?) |
| ERω3FAD (?) | ? | ER | Phospholipid/ Betaine lipid? |
18 | 3 | Δ15 (or ω3)/cis | 18:3Δ6,9,12-PL (-BL?) | 18:4Δ6,9,12,15-PL (-BL?) |
| ERΔ5FAD.1 (*) ERΔ5FAD.2 (?) |
Phatr_46830 Phatr_22459 | ER | Phospholipid/ Betaine lipid? |
20 | 4 | Δ5/cis | 20:4Δ5,8,11,14,17-PL (-BL?) | 20:5Δ5,8,11,14,17-PL (-BL?) |
| ERΔ4FAD | Phatr_22510? | ER | Phospholipid/ Betaine lipid? |
22 | 5 | Δ5/cis | 22:5Δ7,10,13,16,19-PL (-BL?) | 22:6Δ4,7,10,13,16,19-PL (-BL?) |
| FAD6 (*) | Phatr_48423 | Chloroplast membranes | sn1/sn2-MGDG/DGDG + SQDG | 16 | 1 | Δ12/cis | 16:1Δ9-sn2-MGDG/DGDG/SQDG | 16:2Δ9,12-sn1/sn2-MGDG/DGDG/SQDG |
| PlastidΔ6FAD (?) | Phatr_50443 | Chloroplast membranes | sn2-MGDG | 16 | 2 | Δ6/cis | 16:2Δ9,12-sn2-MGDG | 16:3Δ6,9,12-sn2-MGDG |
| Plastidω3FAD/FAD7 (?) | Phatr_41570 | Chloroplast membranes | sn2-MGDG? | 16 | 3 | ω3/cis | 16:3Δ6,9,12-sn2-MGDG | 16:4Δ6,9,12,15-sn2-MGDG |
| FAD4 | Phatr_41301 | Chloroplast membranes | sn2-PG | 16 | 0 | Δ3/trans | 16:0-sn2-PG | 16:1Δ3trans-sn2-PG |
With the following corrected table:
Table 2.
Fatty acid desaturases of Phaeodactylum tricornutum—Characterized or predicted localization and substrate specificity. (*) functionally characterized; (?) based on predictions.
| Name | Gene ID | Subcellular Localization | Main Substrate | Main Product | ||||
|---|---|---|---|---|---|---|---|---|
| Acyl Linked to: | Carbon Number | Presence of Double Bonds | Position and Configuration of the Introduced Double Bond | Overall Structure | Overall Structure | |||
| PAD/SAD | Phatraft_9316 | Chloroplast stroma | ACP | 16 and 18 | 0 | Δ9/cis | 16:0-ACP | 16:1Δ9-ACP |
| ADS | Phatr_28797 | Endomembrane system | CoA | 18? | 0 | Δ9/cis? | 18:0-CoA? | 18:1Δ9-CoA? |
| FAD2 (*) | Phatr_25769 | ER | Phospholipid/ Betaine lipid? |
18 | 1 | Δ12 (or ω6)/cis | 18:1Δ9-PL (-BL?) | 18:2Δ9,12-PL (-BL?) |
| ERΔ6FAD (*) | Phatr_2948 | ER | Phospholipid/ Betaine lipid? |
18 | 2 | Δ6/cis | 18:2Δ9,12-PL (-BL?) | 18:3Δ6,9,12-PL (-BL?) |
| ERω3FAD (?) | ? | ER | Phospholipid/ Betaine lipid? |
18 | 3 | Δ15 (or ω3)/cis | 18:3Δ6,9,12-PL (-BL?) | 18:4Δ6,9,12,15-PL (-BL?) |
| ERΔ5FAD.1 (*) ERΔ5FAD.2 (?) |
Phatr_46830 Phatr_22459 |
ER | Phospholipid/ Betaine lipid? |
20 | 4 | Δ5/cis | 20:4Δ8,11,14,17-PL (-BL?) | 20:5Δ5,8,11,14,17-PL (-BL?) |
| ERΔ4FAD | Phatr_22510? | ER | Phospholipid/ Betaine lipid? |
22 | 5 | Δ4/cis | 22:5Δ7,10,13,16,19-PL (-BL?) | 22:6Δ4,7,10,13,16,19-PL (-BL?) |
| FAD6 (*) | Phatr_48423 | Chloroplast membranes | sn1/sn2-MGDG/DGDG + SQDG | 16 | 1 | Δ12/cis | 16:1Δ9-sn2-MGDG/DGDG/SQDG | 16:2Δ9,12-sn1/sn2-MGDG/DGDG/SQDG |
| PlastidΔ6FAD (?) | Phatr_50443 | Chloroplast membranes | sn2-MGDG | 16 | 2 | Δ6/cis | 16:2Δ9,12-sn2-MGDG | 16:3Δ6,9,12-sn2-MGDG |
| Plastidω3FAD/FAD7 (?) | Phatr_41570 | Chloroplast membranes | sn2-MGDG? | 16 | 3 | ω3/cis | 16:3Δ6,9,12-sn2-MGDG | 16:4Δ6,9,12,15-sn2-MGDG |
| FAD4 | Phatr_41301 | Chloroplast membranes | sn2-PG | 16 | 0 | Δ3/trans | 16:0-sn2-PG | 16:1Δ3trans-sn2-PG |
On page 1330, line 9, “18:3 and 14” should be “18:3 and 18:4”. Line 29, in the title of Section 2.4.10, “The (18:2Δ9,12 → 18:3Δ6,9,12 and 18:3Δ9,12,15 → 18:3Δ6,9,12,15)-Desaturation” should be “The (18:2Δ9,12 → 18:3Δ6,9,12 and 18:3Δ9,12,15 → 18:4Δ6,9,12,15)-Desaturation”. On page 1331, line 6, in the title of Section 2.4.11, “The Question of the (18:2Δ9,12 → 18:3Δ6,9,15 and 18:3Δ6,9,12 → 18:4Δ6,9,12,15)-Desaturation” should be “The Question of the (18:2Δ9,12 → 18:3Δ9,12,15 and 18:3Δ6,9,12 → 18:4Δ6,9,12,15)-Desaturation”. On page 1332, line 1, “E Δ6FAD” should be “ERΔ6FAD”. On page 1335, lines 25–26, in the Conclusions Section, “ERD6FAD, and ERD5FAD” should be “ERΔ6FAD, and ERΔ5FAD”.
These changes have no material impact on the conclusions of our paper. We apologize to our readers for any inconvenience caused.
Reference
- 1.Dolch L.J., Maréchal E. Inventory of fatty acid desaturases in the pennate diatom Phaeodactylum tricornutum. Mar. Drugs. 2015;13:1317–1339. doi: 10.3390/md13031317. [DOI] [PMC free article] [PubMed] [Google Scholar]