Table 2. Results of Whole-Brain Analyses of NCAN rs1064395 Genotype Effects on Local Gray Matter Volume in the Healthy Sample (N=512) and the Patient Sample (N=171).
| Anatomical region | Side | Cluster size | x | y | z | Z-score | |
|---|---|---|---|---|---|---|---|
| Sample 1 (healthy sample) | |||||||
| Cerebellum, FFG | L | 2131 | −27 | −57 | −29 | 4.19 | |
| ITG, MTG, TP | R | 154 | 52 | 2 | −39 | 3.88 | |
| Orbital parts of MidFG, IFG, SFG; SFG, MidFG | L | 427 | −52 | 51 | 12 | 3.84 | |
| IPG, postcentral gyrus | R | 25 | 44 | −37 | 54 | 3.69 | |
| MTG | R | 162 | 69 | −30 | 9 | 3.64 | |
| HC, PHG, amygdala | R | 36 | 15 | −3 | −18 | 3.29 | |
| STG | L | 18 | −52 | −42 | 18 | 3.27 | |
| SFG, MidFG | R | 10 | 22 | 60 | 24 | 3.25 | |
| Calcarine gyrus | L | 25 | −2 | −94 | −9 | 3.24 | |
| ITG, IOG | L | 11 | −56 | −66 | 12 | 3.20 | |
| ITG, FFG | R | 10 | 38 | 3 | −38 | 3.16 | |
| Sample 2 (patient sample) | |||||||
| HC | R | 45 | 16 | −9 | −9 | 3.66 | |
| SFG | R | 11 | 15 | 51 | 19 | 3.32 | |
| Cerebellum | L | 23 | −8 | −39 | −11 | 3.26 | |
Abbreviations: FFG, fusiform gyrus; HC, hippocampus; IFG, inferior frontal gyrus; IOG, inferior occipital gyrus; ITG, inferior temporal gyrus; MidFG, middle frontal gyrus; MTG, middle temporal gyrus; PHC, parahippocampal gyrus; SFG, superior frontal gyrus; STG, superior temporal gyrus; TP, temporal pole.
Coordinates are given in MNI space.